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Hiroaki Sasaki Selected Research

Loeys-Dietz Syndrome

1/2022The differences in surgical long-term outcomes between Marfan syndrome and Loeys-Dietz syndrome.
1/2022Long-term durability of a reimplantation valve-sparing aortic root replacement can be expected in both Marfan syndrome and Loeys-Dietz syndrome.
3/2016Total Aortic Replacement for a 9-Year-Old Boy With Loeys-Dietz Syndrome.
11/2012Surgical experience with aggressive aortic pathologic process in Loeys-Dietz syndrome.
10/2009Mutation of ACTA2 gene as an important cause of familial and nonfamilial nonsyndromatic thoracic aortic aneurysm and/or dissection (TAAD).

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Hiroaki Sasaki Research Topics

Disease

16Aneurysm (Aneurysms)
12/2021 - 02/2006
8COVID-19
06/2022 - 11/2020
6Aortic Dissection
10/2021 - 05/2008
6Aortic Aneurysm (Aneurysm, Aortic)
10/2021 - 08/2008
5Abdominal Aortic Aneurysm
04/2022 - 12/2004
5Loeys-Dietz Syndrome
01/2022 - 10/2009
5Aortic Arch Aneurysm
07/2021 - 05/2012
4Marfan Syndrome (Marfan's Syndrome)
01/2022 - 10/2009
4Endoleak
09/2020 - 01/2017
4Spinal Cord Injuries (Spinal Cord Injury)
06/2020 - 08/2006
3Infections
05/2022 - 01/2008
3Neoplasms (Cancer)
05/2022 - 08/2007
3Pneumonia (Pneumonitis)
01/2022 - 10/2006
3Pathologic Constriction (Stenosis)
01/2022 - 05/2008
3Spinal Cord Ischemia
12/2021 - 08/2010
3Alzheimer Disease (Alzheimer's Disease)
03/2021 - 07/2015
3Stroke (Strokes)
05/2018 - 01/2015
2Familial Thoracic 1 Aortic Aneurysm
01/2022 - 10/2009
2Descending Thoracic Aortic Aneurysm
10/2021 - 06/2020
2Rupture
10/2021 - 10/2006
2Disease Progression
06/2020 - 01/2020
2Mesenteric Ischemia
06/2019 - 10/2007
2Ischemia
06/2019 - 10/2007
2Chronic Obstructive Pulmonary Disease (COPD)
05/2018 - 03/2013
2Pulmonary Hypertension
01/2011 - 10/2006
2Hypothermia
09/2008 - 04/2006
1Hepatitis B
09/2022
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
08/2022
1Dyspnea (Shortness of Breath)
08/2022
1Autoimmune Diseases (Autoimmune Disease)
05/2022
1Bacterial Infections (Bacterial Infection)
05/2022
1Shock
04/2022
1Acute Lung Injury
02/2022
1Lymphoma (Lymphomas)
02/2022
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
02/2022
1Ischemic Stroke
01/2022
1Sleep Initiation and Maintenance Disorders (Insomnia)
01/2022
1Pancreatitis
01/2022
1Aortic Coarctation
12/2021
1Ascending Aorta Aneurysm
12/2021
1False Aneurysm (Pseudoaneurysm)
10/2021
1Atherosclerotic Plaque (Atheroma)
10/2021
1Hemorrhage
03/2021
1Placenta Previa
03/2021
1Thrombosis (Thrombus)
03/2021
1Cardiac Tamponade
01/2021
1Aortic Rupture
01/2021

Drug/Important Bio-Agent (IBA)

4Biomarkers (Surrogate Marker)IBA
05/2022 - 10/2007
3Proteins (Proteins, Gene)FDA Link
06/2022 - 01/2020
3Amyloid (Amyloid Fibrils)IBA
03/2021 - 07/2015
2VaccinesIBA
09/2022 - 08/2022
2Rituximab (Mabthera)FDA Link
02/2022 - 10/2015
2AntibodiesIBA
02/2022 - 12/2021
2Transforming Growth Factor-beta Type I ReceptorIBA
01/2022 - 10/2009
2Warfarin (Coumadin)FDA LinkGeneric
03/2021 - 01/2017
2thioflavin TIBA
03/2021 - 01/2021
2CytokinesIBA
01/2021 - 12/2005
2Transforming Growth Factor-beta Type II ReceptorIBA
11/2012 - 10/2009
2SteroidsIBA
02/2011 - 10/2006
2Polyethylene Terephthalates (Polyethylene Terephthalate)IBA
02/2007 - 10/2006
12019-nCoV Vaccine mRNA-1273IBA
08/2022
1casirivimabIBA
06/2022
1Neutralizing AntibodiesIBA
06/2022
1imdevimabIBA
06/2022
1casirivimab and imdevimab drug combinationIBA
06/2022
1Interleukin-6 (Interleukin 6)IBA
05/2022
1NeopterinIBA
05/2022
1BiopterinsIBA
05/2022
1Blood Glucose (Blood Sugar)IBA
04/2022
1Hemoglobins (Hemoglobin)IBA
04/2022
1C-Reactive ProteinIBA
04/2022
1remdesivirIBA
01/2022
1ORALIT (ORS)IBA
01/2022
1Fibrillin-1IBA
01/2022
1Cytidine Triphosphate (CTP)IBA
01/2022
1EnzymesIBA
01/2022
1Coenzyme A (CoA)IBA
12/2021
1BNT162 VaccineIBA
12/2021
1SaponinsIBA
03/2021
1AntithrombinsIBA
03/2021
1Heparin (Liquaemin)FDA LinkGeneric
03/2021
1Amyloid beta-PeptidesIBA
03/2021
1TriterpenesIBA
03/2021
1Interleukin-8 (Interleukin 8)IBA
01/2021
1HLA-DRB1 Chains (HLA DRB1)IBA
01/2021
1HLA-A Antigens (HLA-A)IBA
01/2021

Therapy/Procedure

15Endovascular Aneurysm Repair
10/2021 - 08/2010
9Cardiopulmonary Bypass (Heart-Lung Bypass)
06/2020 - 05/2003
6Sternotomy
12/2021 - 11/2002
4Therapeutics
02/2022 - 10/2006
4Prostheses and Implants (Prosthesis)
10/2019 - 02/2007
3Thoracotomy
12/2021 - 04/2006
2Operative Surgical Procedures
07/2021 - 06/2017
2Sutures (Suture)
03/2021 - 09/2019
2Catheters
09/2020 - 01/2008
2Stents
10/2019 - 09/2019
2Endarterectomy (Thromboendarterectomy)
01/2011 - 10/2006
1Replantation
01/2022
1Percutaneous Coronary Intervention
01/2022
1Cardiopulmonary Resuscitation (CPR)
01/2021